• Regeneration: Stem cells can replace damaged or dead heart muscle cells, potentially improving heart pumping function.

• Angiogenesis: They can promote the formation of new blood vessels (neovascularization), improving blood flow to the heart tissue.

• Paracrine Effect: Even if stem cells don’t fully turn into new heart cells, they secrete proteins and microRNAs that reduce inflammation, prevent further cell death, and enhance the repair of existing heart tissue.

• Modulation of Immune Response: Stem cells can reduce harmful scarring (fibrosis) and chronic inflammation that worsens heart disease.

Improves Heart Function:

• Stem cell therapy can modestly improve ejection fraction (how much blood the heart pumps out with each beat) in some patients.

Reduces Damage After Heart Attack:

• When given after a heart attack (myocardial infarction), stem cells may limit the size of the damaged area.

Improves Blood Supply:

• By creating new microvessels, stem cells enhance blood flow, relieving angina (chest pain) and other ischemic symptoms.

Delays Heart Failure Progression:

• Stem cell therapy can help strengthen heart muscle in people with chronic heart failure, potentially improving exercise capacity and quality of life.

Yes, stem cell therapy has shown good progress for heart diseases, especially:

• Ischemic heart disease (coronary artery disease): where reduced blood flow damages heart muscle.

• Heart failure: particularly when it results from a prior heart attack.

Stem cells can help by:

• Regenerating or repairing damaged heart muscle.

• Reducing inflammation and scarring (fibrosis).

• Promoting new blood vessel growth, improving blood supply to heart tissue.